Dinuclear zinc(II) complexes containing (benzimidazol-2-yl)benzene that overcome drug resistance in hepatocellular carcinoma cells through induction of mitochondria fragmentation.
نویسندگان
چکیده
Herein we demonstrated that dinuclear zinc complexes could overcome drug resistance in R-HepG2 drug resistance hepatocellular carcinoma cells through induction of mitochondria-mediated apoptosis or by triggering mitochondria fragmentation, depletion of the membrane potential and intracellular ATP levels.
منابع مشابه
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ورودعنوان ژورنال:
- Dalton transactions
دوره 43 19 شماره
صفحات -
تاریخ انتشار 2014